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Vinay K. Malviya M.D – Immunotherapy In Gynecologic Cancer


Gynecologic Cancer

Cancer is the excessive growth of cells, and gynecologic cancer affects the female reproductive organs. It usually begins in a woman’s pelvis between the stomach and hip bones. Common symptoms of gynecologic cancer are pressure or pain in the pelvic region and vulva itching, irritation, and burning.

However, gynecologic cancer is also characterized by changes in vulva skin color, leading to sores, rashes, warts, and ulcers. According to Vinay K. Malviya M.D, a qualified and experienced health professional, gynecologic cancer can increase urination episodes, and cause constipation, bloating, and diarrhea.

Sometimes, it also causes abnormal vaginal discharge and bleeding. The patient may also experience severe pain in the abdomen and spine. Vulvar, vaginal uterine, ovarian, and cervical are common types of gynecologic cancer. In addition, fallopian tube cancer is another type of gynecologic cancer, but this rarely occurs.

Although cancer has different treatments available, immunotherapy has gained popularity in recent years, thanks to fewer side effects and complications. It uses a person’s immune system to combat cancer cells.

Vinay K. Malviya M.D says that health professionals perform immunotherapy in various ways, such as stimulating or boosting a person’s natural defense mechanisms to attack cancer cells. Read on!

Immunotherapy In Gynecologic Cancer

Immunotherapy is an evidence-based, advanced, cutting-edge treatment for cancer treatment. It strengthens your body’s immune system to identify, target, control, fight, and kill cancer cells. Immunotherapy drugs, vaccines, and other medications can help your immune system:

  • Attack cancer cells without affecting the healthier ones
  • Constantly adapt to changes in the cancer cells
  • Reassess the condition of the cells to modify the attack strategy
  • Kill cancer cells even if it recurs without harming the healthy ones
  • Strengthen the immune system to boost cancer-killing capabilities
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Health professionals use immunotherapy treatment with other therapies, such as chemotherapy, surgery, radiation, or targeted therapies, leading to increased effectiveness and reliability. Let us discuss a few categories of immunotherapy for gynecologic cancer.

Cancer Vaccines

Vinay K. Malviya M.D says cancer vaccines have two categories: cancer treatment and cancer prevention. Today, the medical sector has made available various cancer prevention vaccines.

Likewise, treatment vaccines are also available, but most are under research and investigation. Scientists make efforts to determine whether treatment vaccines can identify and kill specific cancers, such as gynecologic cancer.

T-Cell Therapy

T-Cell Therapy is another type of immunotherapy used for treating cancer cells. The procedure involves extracting the patient’s T-cells from the blood and adding a laboratory-made receptor to these cells. A health professional inserts the T-cells with a receptor back into the patient’s body. These receptors identify, recognize, and kill cancer cells.

Monoclonal Antibodies

According to Vinay K. Malviya M.D, monoclonal antibodies are another type of immunotherapy category that involves the development of antibodies in the laboratory. These antibodies slow the growth of cancer cells by preventing the abnormal proteins from developing fast.

Immunotherapies for Ovarian Cancer

Avastin, also known as Bevacizumab, is a targeted antibody drug used for ovarian cancer treatment. An anti-angiogenic monoclonal antibody targets the VEGF and VEGFR pathway and prevents blood vessels from developing a tumor.

The primary function of this immunotherapy drug is to stop the blood flow to the cancer cells, preventing them from growing faster. Most health professionals combine this treatment with chemotherapy for more effectiveness.

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Immunotherapies for Cervical Cancer

According to Vinay K. Malviya M.D, Tivdak, also known as Tisotumab Vedotin, is an immunotherapy drug used for cervical cancer treatment. It is an antibody-based medication that targets tissue factors to stop cervical tumors’ growth.

Besides, Keytruda or Pembrolizumab is another monoclonal antibody that plays a critical role in blocking the PD-1 proteins on cancer cells developed in a woman’s cervical region.

The purpose is to prevent cancer cells from behaving as normal or healthy cells. Likewise, the antibody allows the T-cells to quickly speed up their process and attack/kill cancer cells.

Final Words

Immunotherapy is promising cancer prevention or treatment methodology. Several immunotherapy drugs and vaccines are available for gynecologic cancers, such as ovarian, cervical, and vaginal cancer.

Common side effects of immunotherapy for gynecologic cancer patients are flu, cough, rash, diarrhea, nausea, fatigue, headaches, body aches, and inflammation. However, these side effects are manageable and do not lead to complications.


Scoopearth Team

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