Top 10 Pharma companies in USA {2021)
Top 10 Pharma companies in USA {2021)

Top 10 Pharma companies in USA {2021}

The United States is the largest market for pharmaceuticals in the world. The American and Canadian pharmaceutical markets alone make up nearly half of the total world pharmaceutical market. Here will be sorted top 10 pharmaceutical companies in the United States.

In 2014 pharmaceutical companies in the United States generated more than $440 billion. In 2019 5 of the world’s 10 largest pharmaceutical companies were in the United States. In the future pharmaceutical companies will experience mergers and acquisitions because the competition is getting tougher.

The pharmaceutical industry has a number of unusual characteristics, both in its structure and in the nature of its business operations, which are little known outside the industry but which materially affect the process of bringing new pharmaceuticals to the patient. The development of a new pharmaceutical is very time-consuming, extremely costly, and high risk, with very little chance of a successful outcome. The process of research and development is described, together with all its challenges, including environmental ones. The commercial realities and constraints of the business, together with its current problems, are discussed, followed by an exploration of some of the likely future commercial and technical developments in the business, including the development of a greener pharmacy

Here the list of the top 10 pharmaceutical industries in the USA

Johnson & Johnson

Founded in 1886, Johnson & Johnson develops pharmaceuticals, medical devices, and other consumer products. This American pharmaceutical company is headquartered in New Brunswick, New Jersey, and has more than 250 subsidiaries in more than 60 countries, with over 132,000 employees.

Since 2012, J&J has been ranked 1st in the world’s pharmaceutical and biotechnology companies. This pharmaceutical company generates $82,059 billion. The company is also producing a Covid-19 vaccine which is very efficient. And also help many nations to dropdown the covid surge

Pfizer Inc

Pfizer is an American multinational company headquartered in New York. The company is one of the largest companies and operates 2 divisions, namely Pfizer Innovative Health (IH) and Pfizer Essential Health (EH). The company manufactures vaccines, immunology products, pharmaceuticals, cardiology, endocrinology, and neurology.

The company is also producing a Covid-19 vaccine which is very efficient. And also help many nations to dropdown the covid surge

It is also the largest pharmaceutical company in the United States

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Pfizer is one of the largest pharmaceutical companies in the United States

In 2019 Pfizer generated $51.8 billion. Become the number 2 pharmaceutical company for 4 consecutive years in the United States behind Johnson & Johnson

Merck & Co.

Merck & Co was founded in 1891 and is one of the largest pharmaceutical companies in the world. The company is headquartered in Kenilworth, New Jersey, and is known to manufacture therapeutic drugs for autoimmune, cholesterol, cancer, and other diseases. The company also produces medicines for animals.

In 2019 Merck had revenues of $46.8 billion dollars. Outside Canada and the United States

Merk and co also in the race of making covid drug but after having many unsuccessful trials company drop the project and said “the company said that it was actively discussing with governments how to help its competitors make their shot”. 

Abbvie Inc

Abbvie Inc. is an American pharmaceutical company focused on biotechnology products, founded in 2013 in Lake Bluff, Illinois, United States. This company produces biological drug products and small molecule drugs.

In 2019 Abbvie Inc generated $33.27 billion 

On 25 June 2019, AbbVie announced it would acquire Irish-based Allergan plc for about $63 billion; however the transaction would not be structured as a tax inversion, and that post the transaction, AbbVie (and the group) would remain legally domiciled in the U.S. for tax purposes

AbbVie’s acquisition of Allergan plc violated the anti-trust rule by the Federal Trade Commission on September 4, 2020. In July, the company announced it would acquire Mavupharma, boosting its cancer drug pipeline.

In May 2021, Allergan Aesthetics announced it would acquire Soliton. In June, Abbvie announced it would acquire TeneoOne and its lead compound TNB-383B. The compound is a BCMA-targeting immunotherapeutic for relapsed or refractory multiple myeloma

Bristol Myer Squibb

The American pharmaceutical company Bristol Myer Squibb is headquartered in New York City. It is a multinational company committed to improving the health of patients worldwide. Bristol Myer Squib (BMS) manufactures prescription drugs, biologic drugs, cancer drugs, HIV/AIDS drugs, cardiovascular drugs, diabetes, hepatitis, and others.

In 2019 BMS generated revenue of $26.15 billion 

Rather than focusing on the covid-19 vaccine, BMB has other plans. Bristol Myers has weighed up that tough environment and decided to make a play for the COVID-19 antibody market. The deal will see Bristol Myers secure global rights to two antibodies in return for an undisclosed financial package.

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Abbot Laboratories

Abbot Laboratories is ranked 6th by US pharmaceutical companies. The pharmaceutical company is headquartered in Abbott Park Lake Bluff, Illinois. The company was founded in 1888 and manufactures pharmaceuticals, medical devices, and nutritional products.

The company’s products also exist for diagnosing and monitoring diseases such as HIV, hepatitis, cancer, and heart medications.

In 2019 this company generated $31.9 billion. However, in 2020 in 3 quarters it generated $23.9 billion dollars.

Rather than focusing on the covid-19 vaccine Abbot has other plans. Abbot laboratories played in covid testing kits and became a major player in the manufacturing of covid-19 testing kits 


The company was formerly known as Applied Molecular Genetic Inc. Amgen was founded in Thousand Oaks California in 1980. Today it is one of the largest biotechnology companies in the world.

In 2019 Amgen generated revenue of $23.4 billion 

Amgen is a pioneer in biotechnology

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology innovator since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world, and is developing a pipeline of medicines with breakaway potential.

Gilead Sciences

Gilead Sciences, Inc. is an American biopharmaceutical company headquartered in Foster City, California. Gilead Sciences operates not only in the United States, but on three continents: North America, Europe, and Australia.

After initially focusing heavily on anti-viral drugs used in the treatment of HIV, hepatitis B, hepatitis C, and influenza, the multinational biopharmaceutical company expanded its product line after acquiring two smaller pharmaceutical companies that concentrate on the treatment of lung diseases.

Gilead generated $22.1 billion in revenue in 2019 and has 11,800 employees

Gilead is in a race of making covid-19 vaccine currently their vaccine is in the phase-3 trial  

Eli Lilly and Company

Known simply as Lilly, the American pharmaceutical company, founded in 1876, is headquartered in Indianapolis, Indiana, with offices in 18 other countries. Lilly was the first company to mass-produce the Salk penicillin, insulin, and polio vaccine.

They are currently the largest psychiatric drug manufacturer and manufacture Prozac (fluoxetine), Dolophine (methadone), Cymbalta (duloxetine), and Zyprexa (olanzapine), and their products are sold in approximately 125 countries.

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In 2019, Lilly generated $22.3 billion in revenue. First-quarter 2020 revenue of $5.86 billion, an increase of 15% compared to the first quarter of 2019.


Biogen Inc. is an American multinational biotechnology company based in Massachusetts. Founded in 1978 by a small group of visionary scientists, the company discovers, develops, manufactures, and markets innovative therapies for the global patient population with neurological and neurodegenerative diseases. Biogen also produces and commercializes biosimilars from advanced biology. Today, Biogen is one of the oldest independent biotechnology companies in the world.

Biogen generated $10.59 billion in the first three quarters of 2020 making it number 10 on the list of the top 10 pharmaceutical companies in the United States.


The pharma sector is in the golden age A research by Deloitte shows that

“ Researchers from the Deloitte Center for Health Solutions interviewed 14 thought leaders (futurists, venture capitalists, digital health leaders, and academics) to find out how they expected the identification, prevention, and treatment of disease to evolve between now and 2040. Through these interviews, five forces emerged that could alter the course of the biopharmaceutical sector. These forces represent both opportunities and threats to incumbents. They include prevention and early detection, custom treatments and personalized medicine, curative therapies, digital therapeutics, and precision intervention. Interviewees noted that disruption is already taking place in the industry, and they tried to project where those threats might lead over the next 20 years.

The forces of change highlighted in this paper are likely to reshape, if not shrink, the market for biopharma products. Biopharma companies should consider the potential for disruption by these forces as they redefine the types of products and solutions they will offer, where they will compete, and the new capabilities they will require. Company leaders should develop strategies to counter potential threats and take advantage of the short- and long-term opportunities that emerge in this changing environment. Organizations that ignore these forces and maintain the status quo could wind up shrinking in parallel to the demand for drug interventions to manage symptomatic diseases.”

Pharma Sector is not going in a loss in anywhere soon. The stock price is rising 

market capitalization increased in pandemic 

In short: Pharma company is in their golden period



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